MMRI wishes everyone a safe and happy holiday season. As we reflect on the year, we are grateful for the continued support of our community, whose generosity and dedication help advance groundbreaking biomedical research to enable tomorrow’s cures.

This holiday season, we are grateful for our community and those who have made it possible for MMRI scientists to continue their research.

Here are just a few highlights from MMRI’s impactful research in 2025:

· Dr. Maria Kontaridis published a transformative study in Science Signaling, identifying PTP1B, a key regulator of the heart’s energy balance, as a molecular switch that determines whether the heart uses fat or sugar as fuel.

· Dr. Matthew Nystoriak has uncovered groundbreaking insights into heart health in a study titled, Cardiac Ketone Body Oxidation Enhances Exercise Performance, published in Circulation Research.

· Dr. Tongbin Wu published a groundbreaking paper in Circulation Research identifying two essential heart-protecting proteins, RBPMS and RBPMS2.

· Dr. Chase Kessinger has received a major national grant to spend the next five years utilizing advanced imaging and novel treatment methods to enhance the detection and treatment of life-threatening blood clots in the lungs.

· Dr. Zhiqiang Lin secured an American Heart Association grant to advance urgently needed research on fatty liver disease.

· Dr. Jason McCarthy received a Department of Defense grant improve monitoring for transplant patients.

If you would like to make a donation to contribute toward MMRI’s innovative research or if you would like to learn more about the research we are conducting, visit https://www.mmri.edu/.